Download or read book Horizon in Frontotemporal Lobar Degeneration Related Disorder written by Liyong Wu and published by Frontiers Media SA. This book was released on 2023-10-16 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontotemporal lobar degeneration (FTLD) encompasses a spectrum of focal neurodegenerative disorders with progressive atrophy of the frontal and temporal lobes. FTLD-related disorders are heterogeneous clinical conditions characterized by social dysfunction and personality changes as well as impairments in language, executive and motor functions. Current clinical diagnostic criteria characterize specific manifestations of FTLD, including transtemporal behavioral dementia (bvFTD), primary progressive aphasia with agrammatic variant (avPPA) and semantic variant (svPPA) subtypes, and movement disorders, including progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and FTD with amyotrophic lateral sclerosis (FTD-ALS).