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The optimization of pharmacokinetic properties has become the bottleneck and a major challenge in drug research. There was, hence, an urgent need for a book cov
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Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulati
Dose Optimization in Drug Development
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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug
Pharmacokinetics and Metabolism in Drug Design
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In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high th
Lead Optimization for Medicinal Chemists
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Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicin