Jak-Stat Signaling : From Basics to Disease

Jak-Stat Signaling : From Basics to Disease
Author :
Publisher : Springer Science & Business Media
Total Pages : 451
Release :
ISBN-10 : 9783709108918
ISBN-13 : 3709108918
Rating : 4/5 (18 Downloads)

Book Synopsis Jak-Stat Signaling : From Basics to Disease by : Thomas Decker

Download or read book Jak-Stat Signaling : From Basics to Disease written by Thomas Decker and published by Springer Science & Business Media. This book was released on 2012-06-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies and cancer. This book provides comprehensive insights into the latest basic and clinical developments in the field. The first part reviews recent findings and new technologies pertaining to basics of Jak-Stat function. The second part describes the evolution of Jak-Stat signaling and the role of the pathway in invertebrate organisms. The third part focuses on Jak-Stat signaling in hematopoietic cells under both physiological and pathophysiological conditions. Finally, chapters in the fourth section describe the relationship of Jak-Stat signaling to various states of disease, particularly infection, leukemias and solid cancers. The book is intended for all scientists in molecular biology, biochemistry and cell biology dealing with biomedical issues.


Jak-Stat Signaling : From Basics to Disease Related Books

Jak-Stat Signaling : From Basics to Disease
Language: en
Pages: 451
Authors: Thomas Decker
Categories: Science
Type: BOOK - Published: 2012-06-06 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulat
Biologic and Systemic Agents in Dermatology
Language: en
Pages: 567
Authors: Paul S. Yamauchi
Categories: Medical
Type: BOOK - Published: 2018-01-02 - Publisher: Springer

DOWNLOAD EBOOK

Written by leading experts in the field and designed for dermatologists and residents, this book includes evidence-based medicine that underscores the clinical
JAK-STAT Pathway in Disease
Language: en
Pages: 191
Authors: Jr., Richard H. Bell
Categories: Medical
Type: BOOK - Published: 2009-06-11 - Publisher: CRC Press

DOWNLOAD EBOOK

This book reviews current understanding of the biological roles of the signal transducer and activator of transcription (STAT) proteins and their dysregulation
Moderate to Severe Psoriasis
Language: en
Pages: 422
Authors: John Koo
Categories: Medical
Type: BOOK - Published: 2014-03-18 - Publisher: CRC Press

DOWNLOAD EBOOK

Written by experts in the dermatology field, this new fourth edition of Moderate-to-Severe Psoriasis discusses the current use of biologics and other pharmacolo
Encyclopedia of Inflammatory Diseases
Language: en
Pages: 0
Authors:
Categories: Medical
Type: BOOK - Published: 2016-09-15 - Publisher: Birkhäuser

DOWNLOAD EBOOK

Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood