Phosphodiesterases: CNS Functions and Diseases

Phosphodiesterases: CNS Functions and Diseases
Author :
Publisher : Springer
Total Pages : 475
Release :
ISBN-10 : 9783319588117
ISBN-13 : 3319588117
Rating : 4/5 (17 Downloads)

Book Synopsis Phosphodiesterases: CNS Functions and Diseases by : Han-Ting Zhang

Download or read book Phosphodiesterases: CNS Functions and Diseases written by Han-Ting Zhang and published by Springer. This book was released on 2017-09-26 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.


Phosphodiesterases: CNS Functions and Diseases Related Books

Phosphodiesterases: CNS Functions and Diseases
Language: en
Pages: 475
Authors: Han-Ting Zhang
Categories: Medical
Type: BOOK - Published: 2017-09-26 - Publisher: Springer

DOWNLOAD EBOOK

PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and
cGMP: Generators, Effectors and Therapeutic Implications
Language: en
Pages: 581
Authors: Harald H. H. W. Schmidt
Categories: Science
Type: BOOK - Published: 2008-12-17 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became
Mechanisms of Neuroinflammation
Language: en
Pages: 320
Authors: Gonzalo Emiliano Aranda Abreu
Categories: Medical
Type: BOOK - Published: 2017-08-23 - Publisher: BoD – Books on Demand

DOWNLOAD EBOOK

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose thei
Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health
Language: en
Pages: 638
Authors: Suresh C Sikka
Categories: Medical
Type: BOOK - Published: 2017-11-14 - Publisher: Academic Press

DOWNLOAD EBOOK

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men's reproductive and sexual health with eight s
Frontal-subcortical Circuits in Psychiatric and Neurological Disorders
Language: en
Pages: 474
Authors: David G. Lichter
Categories: Psychology
Type: BOOK - Published: 2001-01-01 - Publisher: Guilford Press

DOWNLOAD EBOOK

The authors review knowledge on the anatomy of the frontal-subcortical circuits, their connections to other brain regions, and their influences on motor, cognit