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New genomic information has revealed the crucial role that protein–protein interactions (PPIs) play in regulating numerous cellular functions. Aberrant forms
Protein Interactions as Targets in Drug Discovery
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Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target prot
Modular Protein Domains
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Authors: Giovanni Cesareni
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Since the full functionality of any given protein can only be understood in terms of its interaction with other, often regulatory proteins, this unique referenc
Proteomics and Protein-Protein Interactions
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The rapidly evolving field of protein science has now come to realize the ubiquity and importance of protein-protein interactions. It had been known for some ti
Protein-Protein Interactions as New Drug Targets
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Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly spec