The BALB/c Mouse

The BALB/c Mouse
Author :
Publisher : Springer
Total Pages : 0
Release :
ISBN-10 : 3642707424
ISBN-13 : 9783642707421
Rating : 4/5 (24 Downloads)

Book Synopsis The BALB/c Mouse by : Michael Potter

Download or read book The BALB/c Mouse written by Michael Potter and published by Springer. This book was released on 2011-12-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mouse was first used in immunological research by Paul Ehrlich in 1891 in an extraordinary series of experiments on the maternal transfer of antitoxic immunity. A short 22 years later in 1913 Halsey Bagg acquired a stock of albino mice from a commercial dealer and used them in a series of experiments on learning. Because he was interested in the genetics of intelligence, Halsey Bagg began breeding a pedigreed line of these mice that were subsequently named for him - Bagg Albino. Though Halsey Bagg is not credited with initiating the inbred strains of mice, his stock curiously has played an indisputably important role. Bagg Albinos were progenitors of the present day BALB/c family of sublines - the subject of this book. They were also used as one of the parents in the development of inbred strains A, CBA and C3H, three other very famous strains. Today the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research. The hallmark of the BALB/c response to so many kinds of infections is susceptibility and sometimes an exaggerated susceptibility, but this paradoxically is not associated with immunodeficiency as BALB/c is an excellent responder to immuni zation. These characteristics have made the BALB/c mouse a model for identifying genes that determine susceptibility to infectious and neoplastic diseases. In 1985 the laboratory BALB/c mouse became 72 years old. The current filial generations are somewhere around 350 generations [MURPHY].


The BALB/c Mouse Related Books

The BALB/c Mouse
Language: en
Pages: 0
Authors: Michael Potter
Categories: Medical
Type: BOOK - Published: 2011-12-06 - Publisher: Springer

DOWNLOAD EBOOK

The mouse was first used in immunological research by Paul Ehrlich in 1891 in an extraordinary series of experiments on the maternal transfer of antitoxic immun
Mouse Genetics
Language: en
Pages: 362
Authors: Professor of Molecular Biology Lee M Silver, Professor Dr
Categories: Medical
Type: BOOK - Published: 1995 - Publisher: Oxford University Press on Demand

DOWNLOAD EBOOK

Mouse Genetics offers for the first time in a single comprehensive volume a practical guide to mouse breeding and genetics. Nearly all human genes are present i
Mouse Models of Innate Immunity
Language: en
Pages: 0
Authors: Irving C. Allen
Categories: Medical
Type: BOOK - Published: 2016-08-27 - Publisher: Humana

DOWNLOAD EBOOK

The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function
The Mouse in Animal Genetics and Breeding Research
Language: en
Pages: 376
Authors: Eugene J. Eisen
Categories: Science
Type: BOOK - Published: 2005 - Publisher: World Scientific

DOWNLOAD EBOOK

The sequencing of the mouse genome has placed the mouse front and center as the most important mammalian genetics model. However, no recent volume has detailed
Methods of Behavior Analysis in Neuroscience
Language: en
Pages: 341
Authors: Jerry J. Buccafusco
Categories: Medical
Type: BOOK - Published: 2000-08-29 - Publisher: CRC Press

DOWNLOAD EBOOK

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeuti