The Role of AAA+ Proteins in Protein Repair and Degradation

The Role of AAA+ Proteins in Protein Repair and Degradation
Author :
Publisher : Frontiers Media SA
Total Pages : 287
Release :
ISBN-10 : 9782889456567
ISBN-13 : 2889456560
Rating : 4/5 (67 Downloads)

Book Synopsis The Role of AAA+ Proteins in Protein Repair and Degradation by : James Shorter

Download or read book The Role of AAA+ Proteins in Protein Repair and Degradation written by James Shorter and published by Frontiers Media SA. This book was released on 2018-12-06 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: ATPases Associated with diverse cellular Activities (AAA+) comprise a superfamily of proteins that are defined by the presence of the AAA+ domain containing canonical Walker A and B motifs required for ATP binding and hydrolysis. Members of this superfamily act on other proteins, DNA, RNA, or multicomponent complexes to affect their conformation or their assembly. There have been substantial advances in understanding the structure and mechanism of function of a large number of AAA+ proteins. In this Research Topic, review articles and original research papers discuss new aspects as well as provide a detailed overview of several AAA+ proteins, namely: ClpXP, Lon, ClpB, Hsp104, p97, AAA+ proteins of the proteasome, Rubisco activases, Torsin, Pontin, and Reptin.


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