Download or read book Constructing an Intermediate Filament Network in Vivo written by Lynne Chang and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: IF play numerous roles in major cellular processes that include cell motility, the determination and maintenance of cell shape, cell signaling, and are major determinants of the mechanical properties of cells. Combined with their cell type and differentiation specific expression, it is clear that they play an important role in tailoring the cytoplasmic environment and architecture for each cell type. Increasing our knowledge of the assembly and maintenance of IF networks in vivo will be crucial for understanding the cytoskeletons' roles in cell physiological processes.