Download or read book Determining discriminating concentrations of insecticides for monitoring resistance in sand flies written by World Health Organization and published by World Health Organization. This book was released on 2023-01-10 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: The document presents outcome of a WHO multi-centre study (2020–2022) performed by eight laboratories in different WHO regions and the WHO expert consultations that made recommendations to WHO on insecticide discriminating concentrations (DCs) for monitoring resistance in sand fly vectors of leishmaniases. It describes use of the WHO bottle bioassay as a new method for testing susceptibility of sand flies to insecticides that are not suitable for impregnation on filter papers and makes recommendations to WHO on monitoring of insecticide resistance in field populations of sand flies. It also proposes further research to test the new DCs for sand flies in other settings and conditions and to collect evidence from the national disease control programmes and share them with WHO for further assessment and revision of the DCs if required. The current edition of the WHO manual for monitoring insecticide resistance in mosquito vectors and selecting appropriate interventions will be revised using the recommendations made to WHO including for the new DCs for sand flies. The report will be useful to the national vector-borne disease control programmes and the research community for resistance monitoring, and to academia, the pesticide regulatory agencies and the pesticide industry for further innovation in this area and to address the research questions. Please send your suggestions and comments to [email protected] indicating the title of the report and the relevant section and page.