Download or read book Pharmaceutical Aspects of Oligonucleotides written by Patrick Couvreur and published by CRC Press. This book was released on 2003-09-02 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses. Aiming to improve the administration of compounds, the book studies the development of nucleotide chemistry.